Chikungunya Virus Net is the web resource for anyone interested in chikungunya. The objectives of Chikungunya Virus Net are to be the public and professional information resource for chikungunya and to serve as a network in the exchange of information and news related to chikungunya.

Chikungunya virus (CHIKV) is an insect-borne virus, of the genus Alphavirus, that is spread by Aedes mosquitoes. Chikungunya infection causes fever and severe joint pain. Other symptoms include muscle pain, headache, nausea, fatigue and rash. The disease shares some clinical signs with dengue, and can be misdiagnosed in areas where dengue is common. There have been recent breakouts of chikungunya in Africa, Asia and the Indian subcontinent. In recent decades mosquito vectors of chikungunya have spread to Europe and the Americas. In 2007, disease transmission was reported for the first time in Europe. There is no cure for the disease. Treatment is focused on relieving the symptoms.

• Mosquito-borne chikungunya threat growing - Tbo.com
  Mon, 28 Jul 2014 03:10:
• Tobago clean-up today to combat chikungunya virus - Trinidad & Tobago Express
  Mon, 28 Jul 2014 02:51:
• San Antonio confirms case of Chikungunya virus - KENS 5 TV
  Sun, 27 Jul 2014 21:21:
• Chikungunya Vaccine Developments Promising - Guardian Liberty Voice
  Sun, 27 Jul 2014 17:31:
• Chikungunya, the new mosquito threat - Seacoastonline.com
  Sun, 27 Jul 2014 06:30:
• Chikungunya continuing to spread - Examiner.com
  Sat, 26 Jul 2014 19:15:
• New Suspected Case of Chikungunya Virus - Your-Story.org
  Sat, 26 Jul 2014 17:41:
• Recent traveller tested for the feared chikungunya virus - Royal Gazette
  Sat, 26 Jul 2014 11:07:
• Mosquito-borne disease chikungunya hits U.S. - The Free Lance-Star
  Sat, 26 Jul 2014 03:18:
• Chikungunya virus confirmed in American Samoa - Radio New Zealand
  Fri, 25 Jul 2014 21:33:

• PRO/EDR> Chikungunya (42): American Samoa
  Mon, 28 Jul 2014 00:43:27
  Chikungunya -- American Samoa [USA]
  The Health Department in American Samoa says it has confirmed the acute rash outbreak as cases of chikungunya, [infection by] a virus similar to dengue fever [clinically and epidemiologically, but in a different virus family - Mod.TY].
  The 3 samples sent off island for testing have been confirmed as the virus, which are the 1st confirmed cases of chikungunya [virus infection] in American Samoa.
  The virus is transmitted to people by mosquitoes, with the most common symptoms being fever

• Monoclonal antibody targeting chikungunya virus envelope 1 protein inhibits virus release.
  Masrinoul P, Puiprom O, Tanaka A, et al. Monoclonal antibody targeting chikungunya virus envelope 1 protein inhibits virus release. [JOURNAL ARTICLE]Virology 2014 Jul 23.:111-117.Chikungunya virus (CHIKV) causes an acute clinical illness characterized by sudden high fever, intense joint pain, and skin rash. Recent outbreaks of chikungunya disease in Africa and Asia are a major public health concern; however, there is currently no effective licensed vaccine or specific treatment. This study reported the development of a mouse monoclonal antibody (MAb), CK47, which recognizes domain III within the viral envelope 1 protein and inhibited the viral release process, thereby preventing the production of progeny virus. The MAb had no effect on virus entry and replication processes. Thus, CK47 may be a useful tool for studying the mechanisms underlying CHIKV release and may show potential as a therapeutic agent.


• Detection of East/Central/South African Genotype of Chikungunya Virus in Myanmar, 2010.
  Tun MM, Thant KZ, Inoue S, et al. Detection of East/Central/South African Genotype of Chikungunya Virus in Myanmar, 2010. [JOURNAL ARTICLE]Emerg Infect Dis 2014 Aug; 20(8):1378-1381.In 2010, chikungunya virus of the East Central South African genotype was isolated from 4 children in Myanmyar who had dengue-like symptoms. Phylogenetic analysis of the E1 gene revealed that the isolates were closely related to isolates from China, Thailand, and Malaysia that harbor the A226V mutation in this gene.


• Preparedness for Threat of Chikungunya in the Pacific.
  Roth A, Hoy D, Horwood PF, et al. Preparedness for Threat of Chikungunya in the Pacific. [JOURNAL ARTICLE]Emerg Infect Dis 2014 Aug; 20(8)Chikungunya virus (CHIKV) caused significant outbreaks of illness during 2005-2007 in the Indian Ocean region. Chikungunya outbreaks have also occurred in the Pacific region, including in Papua New Guinea in 2012; New Caledonia in April 2013; and Yap State, Federated States of Micronesia, in August 2013. CHIKV is a threat in the Pacific, and the risk for further spread is high, given several similarities between the Pacific and Indian Ocean chikungunya outbreaks. Island health care systems have difficulties coping with high caseloads, which highlights the need for early multidisciplinary preparedness. The Pacific Public Health Surveillance Network has developed several strategies focusing on surveillance, case management, vector control, laboratory confirmation, and communication. The management of this CHIKV threat will likely have broad implications for global public health.


• Chikungunya in the Caribbean-Threat for Europe.
  Mansuy JM, Grouteau E, Mengelle C, et al. Chikungunya in the Caribbean-Threat for Europe. [LETTER]Emerg Infect Dis 2014 Aug; 20(8):1423-1425.


• Chikungunya Outbreak in Bueng Kan Province, Thailand, 2013.
  Wanlapakorn N, Thongmee T, Linsuwanon P, et al. Chikungunya Outbreak in Bueng Kan Province, Thailand, 2013. [LETTER]Emerg Infect Dis 2014 Aug; 20(8):1404-1406.


• Movement of Chikungunya Virus into the Western Hemisphere.
  Nasci RS Movement of Chikungunya Virus into the Western Hemisphere. [JOURNAL ARTICLE]Emerg Infect Dis 2014 Aug; 20(8):1394-1395.


• Co-circulation of Dengue and Chikungunya Viruses, Al Hudaydah, Yemen, 2012.
  Rezza G, El-Sawaf G, Faggioni G, et al. Co-circulation of Dengue and Chikungunya Viruses, Al Hudaydah, Yemen, 2012. [JOURNAL ARTICLE]Emerg Infect Dis 2014 Aug; 20(8):1351-1354.We investigated 400 cases of dengue-like illness in persons hospitalized during an outbreak in Al Hudaydah, Yemen, in 2012. Overall, 116 dengue and 49 chikungunya cases were diagnosed. Dengue virus type 2 was the predominant serotype. The co-circulation of these viruses indicates that mosquitoborne infections represent a public health threat in Yemen.


• Local and regional spread of chikungunya fever in the Americas.
  Cauchemez S, Ledrans M, Poletto C, et al. Local and regional spread of chikungunya fever in the Americas. [Journal Article]Euro Surveill 2014; 19(28)


• Large number of imported chikungunya cases in mainland France, 2014: a challenge for surveillance and response.
  Paty M, Six C, Charlet F, et al. Large number of imported chikungunya cases in mainland France, 2014: a challenge for surveillance and response. [Journal Article]Euro Surveill 2014; 19(28)


• Cases of chikungunya virus infection in travellers returning to Spain from Haiti or Dominican Republic, April-June 2014.
  Requena-Mendez A, Garcia C, Aldasoro E, et al. Cases of chikungunya virus infection in travellers returning to Spain from Haiti or Dominican Republic, April-June 2014. [Journal Article]Euro Surveill 2014; 19(28)