Chikungunya Virus Net is the web resource for anyone interested in chikungunya. Chikungunya virus (CHIKV) is an insect-borne virus, of the genus Alphavirus, that is spread by Aedes mosquitoes. Chikungunya infection causes fever and severe joint pain. Other symptoms include muscle pain, headache, nausea, fatigue and rash. The disease shares some clinical signs with dengue, and can be misdiagnosed in areas where dengue is common. There have been recent breakouts of chikungunya in Africa, Asia and the Indian subcontinent. In recent decades mosquito vectors of chikungunya have spread to Europe and the Americas. In 2007, disease transmission was reported for the first time in Europe. There is no cure for the disease. Treatment is focused on relieving the symptoms.

The objectives of Chikungunya Virus Net are to be the public and professional information resource for chikungunya and to serve as a network in the exchange of information and news related to chikungunya.

• Valneva Completes Recruitment for Pivotal Phase 3 Trial of - GlobeNewswire
  Mon, 12 Apr 2021 07:00 GMT
• Brazil: Paraná reports increase in chikungunya cases - Outbreak News Today - Outbreak News Today
  Tue, 20 Apr 2021 07:00 GMT
• Chikungunya Vaccine Candidate: Valneva completes recruitment for Phase 3 trial - Outbreak News Today - Outbreak News Today
  Wed, 14 Apr 2021 07:00 GMT
• Valneva recruits 4,131 US adults for Phase 3 trial of chikungunya vaccine candidate - Homeland Preparedness News
  Wed, 14 Apr 2021 07:00 GMT
• Tracking mosquito larvae to prevent Dengue, Chikungunya spikes - CGTN
  Sun, 02 May 2021 14:48 GMT
• The Caribbean: CARPHA urges the public to protect against mosquito borne diseases like dengue - Outbreak News Today - Outbreak News Today
  Sat, 08 May 2021 21:52 GMT
• Bug Off: Advice for battling feisty mosquitoes this season - WJXT News4JAX
  Wed, 05 May 2021 16:42 GMT
• Chikungunya may affect central nervous system as well as joints and lungs - EurekAlert
  Wed, 04 Nov 2020 08:00 GMT
• Mosquito abatement necessary precaution - Walterboro Live
  Sat, 08 May 2021 21:00 GMT
• CARPHA urges vigilance against mosquito-borne diseases during COVID-19 pandemic - Jamaica Observer
  Thu, 06 May 2021 16:07 GMT
• Structural basis of Chikungunya virus inhibition by monoclonal antibodies - pnas.org
  Tue, 03 Nov 2020 08:00 GMT
• Checking on Chikungunya - NASA - NASA - NASA
  Mon, 27 Jul 2020 07:00 GMT
• CARPHA warns of mosquitoes as rainy season approaches - Nation News
  Fri, 07 May 2021 14:00 GMT
• First genetically modified mosquitoes released in US - Livescience.com
  Wed, 05 May 2021 18:31 GMT
• Daily briefing: Concussion risk is higher for female soccer players - Nature.com
  Tue, 04 May 2021 18:07 GMT

• PRO> Vector mosquito control - USA: (FL)
  Wed, 05 May 2021 17:31:47 -0400
  Other Human Disease -- United States
  After a decade of fighting for regulatory approval and public acceptance, a biotechnology firm has released genetically engineered mosquitoes into the open air in the United States for the first time. The experiment, launched this week in the Florida Keys (over the objections of some local critics), tests a method for suppressing populations of wild _Aedes aegypti_ mosquitoes, which can carry diseases such as Zika, dengue, chikungunya and yellow fever.
  Oxitec, the firm based in Abingdon,

• Identification of juvenile hormone-induced posttranslational modifications of methoprene tolerant and Kruppel homolog 1 in the yellow fever mosquito, Aedes aegypti Thu, 06 May 2021 06:00:00 -0400
  Recent studies reported that JH regulated phosphorylation status of the JH-receptor complex contributes to its transcription activity in Aedes aegypti. However, phosphorylation sites of these proteins have not yet been identified. In this study, we found that the fusion of an EGFP tag to Ae. aegypti Kr-h1 (AaKr-h1) and Met (AaMet) improved their stability in mosquito Aag-2 cells, which allowed their purification. The liquid chromatography and tandem mass spectrometry analysis of the purified...
• Employing Different Traps for Collection of Mosquitoes and Detection of Dengue, Chikungunya and Zika Vector, Aedes albopictus, in Borderline of Iran and Pakistan Thu, 06 May 2021 06:00:00 -0400
  CONCLUSION: The resulting data collected here on the efficiency of the various trap types can be useful for monitoring the densities of mosquito populations, which is an important component of a vector surveillance system. While the presence of Ae. albopictus was determined in this potential risk area, there is no evidence for its establishment and further monitoring needs to be carried out.
• Meningoencephalitis associated with Zika virus and Chikungunya virus infection Thu, 06 May 2021 06:00:00 -0400
  Etiology of viral meningoencephalitis is frequently unidentified. Chikungunya virus (CHIKV) and Zika virus (ZIKV) have been known to affect the central nervous system, and should, therefore, be considered for diagnosis of meningoencephalitis since its outcome may be influenced by the etiologic agent, age and immunological condition of the patient. In this study we aimed to determine if CHIKV and ZIKV were the etiological agent of viral encephalitis in meningoencephalitis patients admitted to the...
• Negeviruses reduce replication of alphaviruses during co-infection Thu, 06 May 2021 06:00:00 -0400
  Negeviruses are a group of insect-specific virus (ISV) that have been found in many arthropods. Their presence in important vector species led us to examine their interactions with arboviruses during co-infections. Wild-type negeviruses reduced the replication of several alphaviruses during co-infections in mosquito cells. Negev virus (NEGV) isolates were also used to express GFP and anti-chikungunya virus (CHIKV) antibody fragments during co-infections with CHIKV. NEGV expressing anti-CHIKV...
• Global patterns of aegyptism without arbovirus Wed, 05 May 2021 06:00:00 -0400
  The world's most important mosquito vector of viruses, Aedes aegypti, is found around the world in tropical, subtropical and even some temperate locations. While climate change may limit populations of Ae. aegypti in some regions, increasing temperatures will likely expand its territory thus increasing risk of human exposure to arboviruses in places like Europe, Northern Australia and North America, among many others. Most studies of Ae. aegypti biology and virus transmission focus on locations...
• Use of Cerebrospinal Fluid for the Diagnosis of Neuroinvasive Dengue, Zika, and Chikungunya: A 19-year systematic review Wed, 05 May 2021 06:00:00 -0400
  CONCLUSIONS: Although cerebrospinal fluid analysis is of great importance for increasing neurological diagnostic accuracy and contributes to the early diagnosis of neuroinvasive dengue, chikungunya, and Zika infections, it is underused in routine laboratory investigations worldwide.
• Analysis of a Routinely Used Commercial Anti-Chikungunya IgM ELISA Reveals Cross-Reactivities with Dengue in Brazil: A New Challenge for Differential Diagnosis? Wed, 05 May 2021 06:00:00 -0400
  In Brazil, chikungunya emerged in 2014, and by 2016, co-circulated with other arbovirosis, such as dengue and zika. ELISAs (Enzyme-Linked Immunosorbent Assays) are the most widely used approach for arboviruses diagnosis. However, some limitations include antibody cross reactivities when viruses belong to the same genus, and sensitivity variations in distinct epidemiological scenarios. As chikungunya virus (CHIKV) is an alphavirus, no serological cross reactivity with dengue virus (DENV) should...
• Mucocutaneous manifestations of Chikungunya fever, an experience of tertiary care hospital Tue, 04 May 2021 06:00:00 -0400
  CONCLUSIONS: Chikungunya fever presented with unusual mucocutaneous findings, some of which remained present months or even years after the onset of chikungunya fever.
• "Kankasha" in Kassala: A prospective observational cohort study of the clinical characteristics, epidemiology, genetic origin, and chronic impact of the 2018 epidemic of Chikungunya virus infection in Kassala, Sudan Fri, 30 Apr 2021 06:00:00 -0400
  CONCLUSIONS/SIGNIFICANCE: Vulnerability to CHIKV remains in Kassala and elsewhere in Sudan due to widespread Aedes aegypti presence and mosquito-fostering household water storage methods. This study highlights the importance of increasing awareness of the severity and impact of CHIKV outbreaks, and the need for urgent actions to reduce transmission risk in households.
• The Impact of Health Risk Communication: A Study on the Dengue, Chikungunya, and Zika Epidemics in Curacao, Analyzed by the Social Amplification of Risk Framework (SARF) Fri, 30 Apr 2021 06:00:00 -0400
  Epidemics of dengue, chikungunya, and Zika have been threatening the Caribbean. Since risk communication (RC) plays a fundamental role in preventing and controlling diseases understanding how RC works is essential for enabling risk-reducing behavior. This multimethod qualitative study compares news reports with local's and health professional's perspectives, currently lacking in RC research. It was found that RC strategies were obstructed by a lack of governmental structure, organization, and...