Chikungunya Virus Net is the web resource for anyone interested in chikungunya. Chikungunya virus (CHIKV) is an insect-borne virus, of the genus Alphavirus, that is spread by Aedes mosquitoes. Chikungunya infection causes fever and severe joint pain. Other symptoms include muscle pain, headache, nausea, fatigue and rash. The disease shares some clinical signs with dengue, and can be misdiagnosed in areas where dengue is common. There have been recent breakouts of chikungunya in Africa, Asia and the Indian subcontinent. In recent decades mosquito vectors of chikungunya have spread to Europe and the Americas. In 2007, disease transmission was reported for the first time in Europe. There is no cure for the disease. Treatment is focused on relieving the symptoms.

The objectives of Chikungunya Virus Net are to be the public and professional information resource for chikungunya and to serve as a network in the exchange of information and news related to chikungunya.

• Emergent BioSolutions begins phase 3 study of chikungunya virus vaccine candidate - Homeland Preparedness News
  Fri, 15 Oct 2021 18:18 GMT
• India Newswire: Nipah, dengue, HIV and chikungunya - Outbreak News Today - Outbreak News Today
  Sun, 17 Oct 2021 18:12 GMT
• Mumbai doctors see a spurt in chikungunya cases - Hindustan Times
  Mon, 27 Sep 2021 07:00 GMT
• Clinical trials show promise for Chikungunya vaccine - Mexico News Daily
  Tue, 28 Sep 2021 07:00 GMT
• Money laundering case: Shiv Sena MP Bhavana Gawali skips ED's summon, suffering from Chikungunya - Times of India
  Wed, 20 Oct 2021 07:43 GMT
• Chikungunya Fever Drugs Market Analysis 2021-2028 | KeyplayersAbivax Sa, Arno Therapeutics Inc, Bharat Biotech International Ltd, Ennaid Therapeutics Llc – Puck77 - Puck77
  Tue, 19 Oct 2021 11:35 GMT
• Pune records 80 chikungunya, 192 dengue cases in September - Hindustan Times
  Mon, 04 Oct 2021 07:00 GMT
• Cases of dengue and chikungunya more than double in city in one month: PMC - The Indian Express
  Sat, 02 Oct 2021 07:00 GMT
• After dengue, chikungunya cases also take wing in Maharashtra and Mumbai - Times of India
  Fri, 24 Sep 2021 07:00 GMT
• Mumbai: Chikungunya cases in city surge by 78.75% - Free Press Journal
  Thu, 14 Oct 2021 21:44 GMT
• Fivefold increase in pediatric chikungunya cases from 2019 in Ahmedabad - Times of India
  Fri, 24 Sep 2021 07:00 GMT
• Co-Diagnostics JV CoSara Receives Clearance from Indian Regulators for Dengue/Chikungunya Multiplex Test - Yahoo Finance
  Wed, 06 Oct 2021 07:00 GMT
• NMC deploys 60 teams to curb dengue, chikungunya cases - Times of India
  Fri, 01 Oct 2021 07:00 GMT
• Taking Aim at Alphaviruses - Global Biodefense
  Tue, 12 Oct 2021 15:31 GMT
• Ahmedabad - LatestLY
  Thu, 14 Oct 2021 17:34 GMT

• PRO/AH/EDR> Rift Valley fever - Sudan: (NO) livestock, human, susp, RFI
  Wed, 15 Sep 2021 20:49:58 -0400
  Rift Valley Fever -- Sudan
  Doctors in Sudan's Northern State have reported 27 deaths and 68 [abortions] among livestock in the area of El Nafaab in Merowe locality and warn of the emergence of cases of Rift Valley fever [RVF] and chikungunya, similar to last year [2020]. They have appealed to the Ministry of Health and the state government to deal with the potential epidemic in a safe manner.
  In a press statement on Sunday [5 Sep 2021], the Socialist Doctors Association reported that a resident of the state arrived

• Climate change and infectious disease in Europe: Impact, projection and adaptation Tue, 19 Oct 2021 06:00:00 -0400
  Europeans are not only exposed to direct effects from climate change, but also vulnerable to indirect effects from infectious disease, many of which are climate sensitive, which is of concern because of their epidemic potential. Climatic conditions have facilitated vector-borne disease outbreaks like chikungunya, dengue, and West Nile fever and have contributed to a geographic range expansion of tick vectors that transmit Lyme disease and tick-borne encephalitis. Extreme precipitation events...
• Bioallethrin activates specific olfactory sensory neurons and elicits spatial repellency in Aedes aegypti Mon, 18 Oct 2021 06:00:00 -0400
  CONCLUSION: Results from this study show that bioallethrin repellency is likely the result of co-activation of Or(s) and sodium channels. These findings not only contribute to the understanding of the modes of action of volatile pyrethroids in spatial repellency, but also provide a framework for developing new repellents based on the dual-target mechanism revealed. This article is protected by copyright. All rights reserved.
• Viral characteristics and clinical presentation in dengue co-infection- Findings from a facility based observational study in Odisha, India Mon, 18 Oct 2021 06:00:00 -0400
  CONCLUSIONS: All the four dengue serotypes were found to be circulating with DEN 2 as the most predominant one. About 5.8% of dengue cases have co-infection (mainly with Chikungunya) and clinically present with atypical signs and symptoms.
• Acute-Phase Levels of CXCL8 as Risk Factor for Chronic Arthralgia Following Chikungunya Virus Infection Mon, 18 Oct 2021 06:00:00 -0400
  The immunopathogenesis of chikungunya virus (CHIKV) infection and the role of acute-phase immune response on joint pain persistence is not fully understood. We investigated the profile of serum chemokine and cytokine in CHIKV-infected patients with acute disease, compared the levels of these biomarkers to those of patients with other acute febrile diseases (OAFD) and healthy controls (HC), and evaluated their role as predictors of chronic arthralgia development. Chemokines and cytokines were...
• Anti-inflammatory effect of Kaba Sura Kudineer (AYUSH approved COVID-19 drug)-A Siddha poly-herbal formulation against lipopolysaccharide induced inflammatory response in RAW-264.7 macrophages cells Fri, 15 Oct 2021 06:00:00 -0400
  CONCLUSIONS: . Together, this study has proven that KSK could be a potential therapeutic drug for alleviating excessive inflammation in many inflammation-associated diseases like COVID-19.
• Indirect transfer of pyriproxyfen to European honeybees via an autodissemination approach Thu, 14 Oct 2021 06:00:00 -0400
  The frequency of arboviral disease epidemics is increasing and vector control remains the primary mechanism to limit arboviral transmission. Container inhabiting mosquitoes such as Aedes albopictus and Aedes aegypti are the primary vectors of dengue, chikungunya, and Zika viruses. Current vector control methods for these species are often ineffective, suggesting the need for novel control approaches. A proposed novel approach is autodissemination of insect growth regulators (IGRs). The advantage...
• Thrombotic microangiopathy associated with arboviral infection: Report of 3 cases Thu, 14 Oct 2021 06:00:00 -0400
  Dengue fever and chikungunya are viral diseases that have spread rapidly throughout the world in recent decades. The occurrence of complications is well known, including prerenal acute kidney injury (AKI), which is usually thought to be caused by dehydration and fluid loss. Thrombotic microangiopathy (TMA) is an uncommon aggravation of dengue fever and chikungunya, with only a few cases described in the medical literature. The aim of this study is to present 3 cases of TMA associated with...
• Sulfasalazine-induced drug reaction with eosinophilia and systemic symptoms (DRESS) with concomitant acute chikungunya virus infection: possible role of new viral trigger Wed, 13 Oct 2021 06:00:00 -0400
  Drug reaction with eosinophilia and systemic symptoms (DRESS) is designated as a potentially lethal adverse drug effect with characteristic signs and symptoms such as skin rash, fever, leucocytosis with eosinophilia or atypical lymphocytes, lymphadenopathy and liver or renal dysfunction. In addition to most commonly implicated drug category (aromatic anticonvulsants), lamotrigine, sulfonamides, dapsone and abacavir may also induce this syndrome. We describe here a case a sulfasalazine-induced...
• An update on the mosquito fauna and mosquito-borne diseases distribution in Cameroon Tue, 12 Oct 2021 06:00:00 -0400
  The expansion of mosquito-borne diseases such as dengue, yellow fever, and chikungunya in the past 15 years has ignited the need for active surveillance of common and neglected mosquito-borne infectious diseases. The surveillance should be designed to detect diseases and to provide relevant field-based data for developing and implementing effective control measures to prevent outbreaks before significant public health consequences can occur. Mosquitoes are important vectors of human and animal...
• Source-tracking of the Chinese Chikungunya viruses suggests that Indian subcontinent and Southeast Asia act as major hubs for the recent global spread of Chikungunya virus Tue, 12 Oct 2021 06:00:00 -0400
  CONCLUSIONS: Here we report a novel CHIKV isolate from a chikungunya patient who came from Myanmar to China in 2019, and summarize the source and evolution of Chinese CHIKV strains. Our present findings provide a better understanding of the recent global evolution of CHIKV, highlighting the urgent need for strengthened surveillance against viral diversity.